Prealbumin, known as transthyretin (TTR), is synthesized primarily in the liver and acts as a binding protein for thyroid hormones and retinol-binding protein. It also acts as a biochemical marker to evaluate liver function, malnutrition, and the efficacy of parenteral nutrition.
Prealbumin / TTR ranges from 21mg/dL to 43 mg/dL in healthy adult males and 17mg/dL to 34 mg/dL in adult females. Decreased levels of prealbumin indicate protein-calorie malnutrition, liver disease, or acute inflammation. Thus, determining the level of prealbumin is a sensitive and cost-effective method of assessing the severity of illness resulting from malnutrition in patients who are critically ill or have a chronic disease. An abnormal level of prealbumin is also associated with other pathological conditions, including certain cancers, infection and sepsis, and end-stage renal disease.
Immunoturbidimetric assay is one of the most commonly used prealbumin detection methods. Creative Diagnostics can support your testing by providing native prealbumin antigens and several monoclonal antibodies. Our new high-affinity mouse monoclonal antibodies have been validated both in ELISA and Immunoturbidimetric. Clones can be paired with each other and are suitable for the development of diagnostics assays.
A prealbumin blood test measures prealbumin levels in your blood. Prealbumin is a protein synthesized in your liver. It helps carry thyroid hormones and vitamin A through your bloodstream as well as regulate energy consumption in the body. If your prealbumin levels are lower than normal, it may be a sign of malnutrition, a condition which your body lacks the calories, vitamins, and/or minerals needed to support normal functions... Learn more
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Creative Diagnostics · 45-1 Ramsey Road · Shirley · New York · 11967
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45-1 Ramsey Road, Shirley, NY 11967, USA
