genotyping, mutant analysis in CRISPR/Cas9 or analysis of single CpG methylation
SNP stands for Single Nucleotide Polymorphism. SNPs are molecular genetic markers (mostly point mutations) that have integrated in the gene pool of a population. SNP's are used in human medicine, agriculture as well as biology to associate sections of the genome with phenotypic traits for diagnostic purposes, breeding and diversity research.
Genaxxon's SNP Pol DNA Polymerase is a highly selective DNA polymerase specifically designed for specific discrimination of alleles or single nucleotides. Thus, it distinguishes between correctly and mismatched primer-template complexes very accurately and only yields PCR products if the primers at the 3' end match the template exactly. Depending on the primer design, both positive and negative selection can be performed.
The SNP Pol DNA polymeraseis therefore ideally suited for SNP detection, genotyping (e.g. HLA), mutant analysis in CRISPR/Cas9 technology or the analysis of single CpG methylation sites.
Test Sample available!
SNP Pol DNA Polymerase 2X PCR master mix
Contains all components necessary for direct PCR or PCR based genotyping.
validating CRISPR/Cas9 controls - validation of NGS sequencing - SNP-detection by allele-specific amplification (ASA) / Allele-specific PCR - allele specific primer extension (AS-PEX) - Methylation specific PCR (MSP) - HLA genotyping - Micro-sequencing.
Genaxxon bioscience’s dNTPs are highly stable, highly pure (>99%, RP-HPLC) nucleoside triphosphates with no detectable bacterial/human DNA, DNases, RNases, nicking activity or proteases. They are available in liquid form as dNTP-Set (100mM) >or dNTP-Mix (10mM > and 2mM >), as powder or in modified versions, e.g. Biotin-11-dUTP >.
