Creative Diagnostics) Selecting Nanoparticles for Lateral Flow Immunoassays (LFIAs)
작성자
abbabio
작성일자
2021-03-26
조회수
389
Selecting Nanoparticles for Lateral Flow Immunoassays (LFIAs)
The materials used as labels in LFIA are very vast, including gold nanoparticles, colored latex beads, magnetic particles, carbon nanoparticles, silver nanoparticles, quantum dots, upconverting nanoparticles, enzymes, and liposomes. Any material used as a label should be detectable at a very low concentration and should retain its characteristics when combined with biometric molecules. This combination is also expected to not change the characteristics of the biometric probe. Easily binding to biomolecules and maintaining stability over a long period of time are ideal characteristics of a good label.
Because of their signal amplification characteristics, nanomaterials are expected to achieve high sensitivity and high selectivity in LFIA, which arouses great interest. There are many examples of LFIAs that combine nanomaterials with immunochromatographic testing, which can be used for clinical, environmental, and food analysis. In this brochure, we briefly evaluate the properties and applications of nanomaterials, hoping to be useful with your selection of nanoparticles for LFIA.
