Quinoxaline, also known as benzopyrazine, is important nitrogen containing heterocyclic compounds, which a ring compound composed of a benzene ring and a pyrazine ring. Its derivatives have gained considerable attention in the field of contemporary medicinal chemistry. The moiety is of substantial importance because of its wide array of pharmacological activities such as anti-tumor, anti-cancer, antimalarial, anti-inflammatory, antimicrobial, anti-HIV etc. Diversely substituted quinoxalines are important therapeutic agents in the pharmaceutical industry[1-6].
A series of medicinal products containing quinoxaline has been firmly incorporated in medical practice.
[1] European Journal of Medicinal Chemistry (2018), 143, 542-557. [2] Journal of Medicinal Chemistry (2020), 63(13), 7243-7251. [3] European Journal of Medicinal Chemistry (2018), 145, 559-569. [4] Journal of Medicinal Chemistry (2010), 53(8), 3296-3304. [5] European Journal of Medicinal Chemistry (2016), 117, 230-240. [6] Journal of Medicinal Chemistry (2009), 52(7), 2148-2152.
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