Creative-diagnostics) Fluorescent Nanoparticles for Intracellular Applications
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2021-04-15
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Fluorescent Nanoparticles for Intracellular Applications
Nanoparticles (NPs) are a subclass of nanomaterials. With their unique properties and great applicability, they are currently at the forefront of cutting-edge research in almost all imaginable fields including biomedicine. The small size of NPs allows them to penetrate biological barriers easily and also be transferred between cells, tissues, and organs. However, like a double-edged sword, their potential risks (i.e., adverse effects) also stem from this ability. How NPs enter cells is also a key factor in determining their biomedical function, biodistribution, and toxicity.
Here, we introduce the fluorescent nanoparticles in cell uptake research and the effects of their physical and chemical properties such as size, shape, charge, and surface chemistry on their internalization by cells.