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ÀÛ¼ºÀÏÀÚ 2021-05-11
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 TRC Cancer Research Tools. View in Browser. 
   
 
 
LGC | trc
  
 Cancer Research Tools - TRC
 
   
 
Toronto Research Chemicals
 
Newsletter
 
 
   
 Dear Researcher,
TRC offers over 12,000 research products for target-specific research interests in cancer. All TRC products are delivered with a complete analytical data package, including full spectroscopic analysis, certificate of analysis, specified chemical purity by NMR, HPLC, MS & elemental analysis. We hope that you find this newsletter to be a valuable source of information.
 
   
 
   
 Explore the TRC range here 
   
 
   
 Please contact us with further questions or product suggestions for other areas of interest to feature, if you can't find what you are looking for. 
   
 
 
 Apoptosis
 
   
 
331244-89-4 | 3-Methyl-1-(4-phenyl-2-thiazolyl)-1H-Pyrazole-4,5-dione  4-[2-(2-Ethoxyphenyl)hydrazone] | BAM7; | C©ü©ûH©û₉N₅O©üS | TRC
 
BAM7
Catalog No: M326965
 
 Specific BH3-binding site proapoptotic BAX activator used in cancer treatment.
 
   
 Read more 
   
 
   
   
   
 
 
 Cancer Immunology
 
   
 
1316695-35-8 | LM 10 |  6-Fluoro-3-[(1E)-2-(2H-tetrazol-5-yl)ethenyl]-1H-indole | C©û©ûH₈FN₅ | TRC
 
LM 10
Catalog No: L469303
 
 An inhibitor of tryptophan 2,3-dioxygenase (TDO) that shows reversal of tumoral immune resistance via this inhibition process.
 
   
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 Cytokines & Epigenetics
 
   
 
642008-81-9 | BRD 6989 |  2-Amino-5,6,7,8-tetrahydro-6-methyl-4-(3-pyridinyl)-3-quinolinecarbonitrile  | C©û₆H©û₆N©þ | TRC
 
BRD 6989
Catalog No: B677688
 
 A small molecule inhibitor with high selectivity for CDK8 over CDK19. Increases IL-10 production in stimulated human and murine macrophages and dendritic cells.
 
   
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 Signal Transduction
 
   
 
19542-67-7 | BAY 11-7082 |  (2E)-3-[(4-Methylphenyl)sulfonyl]-2-propenenitrile;  (E)-3-[(4-Methylphenyl)sulfonyl]-2-propenenitrile;  (E)-3-(p-Tolylsulfonyl)-acrylonitrile; BAY 11-7821; BAY 117821 | C©û₀H₉NO©üS  | TRC
 
BAY 11-7082
Catalog No: B118790
 
 A nuclear factor-¥êB (NF-¥êB) inhibitor and a potential anti-inflammatory agent. Also a potent IKK inhibitor.
 
   
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 Metastasis
 
   
 
 
JLK 6
Catalog No: J211985
 
 An inhibitor of ¥ã-secretase, selectively inhibits ¥âAPP cleavage.
 
   
 Read more 
   
 
 
   
 
       
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