Creative Diagnostics) Antibodies against SARS-CoV-2 Delta Variants
작성자
abbabio
작성일자
2021-08-26
조회수
387
Antibodies against SARS-CoV-2 Delta Variants
The Delta variant hosts multiple mutations in the S1 subunit, including three in the RBD that seem to improve the RBD's ability to bind to ACE2 and evade the immune system. Studies report that the variant replicates faster and at higher levels, explaining why it has much high transmissibility than other variants. Diagnostic testing remains a critical component in managing the spread of COVID-19.
Creative Diagnostics has developed the highly sensitive monoclonal antibody pair against SARS-CoV-2 nucleocapsid that is utilized in commercial lateral flow rapid antigen tests around the world. Using CD's antibodies, all major circulating variants including Delta and Lambda were able to be detected in clinical tests.
Highly sensitive antibody pair that can detect all variants including Lambda and Delta
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Manufactured in multigram quantities weekly
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Used in commercial antigen detection assays worldwide
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No cross-reaction with other respiratory pathogens
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Competitive price for reduced production costs
Resources
Delta, Kappa, and Lambda SARS-CoV-2 Pseudotyped Lentivirus Now Available
Creative Diagnostics has a full range of ready-to-use wild-type and newly emerged mutant SARS-CoV-2 pseudotyped lentiviruses to support the study of the interaction between SARS-CoV-2 spike protein and human ACE2 in a physiologically relevant context.
Creative Diagnostics has developed several neutralizing antibodies against SARS-CoV-2. The activities of these antibodies have been extensively validated in both binding assays, and pseudovirus infection assays.
The SARS-CoV-2 spike CHO-K1 cell line has been developed by the stable transfection of the SARS-CoV-2 spike protein plasmid. SARS-CoV-2 spike CHO-K1 cell line provides consistent levels of __expression__ of the SARS-CoV-2 spike protein on the cell surface.
