—Reliable Alternative to Serum-Based Calibrators and Controls
Creative Diagnostics now offers a newly developed set of humanized monoclonal antibodies (IgM, IgG or IgA) against different viruses that can be used as alternatives to serum-based calibrators, positive, negative, or quality controls in assay development and manufacturing of diagnostic kits.
The antibodies consist of the human constant region of the heavy chain, mouse variable region of the heavy chain and mouse light chain. The human constant region of the heavy chain can be directly recognized by the anti-human conjugate, which is used in numerous in vitro diagnostic assays.
Coronaviruses are a family of enveloped RNA viruses that infect various mammals as well as birds. Of clinical importance is the Human coronaviruses (HCoVs), which belong to the Coronaviridae family.
Antibodies are one of the important reagents in life sciences and clinical medicine. Although antibodies have been widely used, there is a lack of established criteria to guide how they should be validated before use.
Zika virus (ZIKV), formerly a neglected pathogen, has recently been associated with microcephaly in fetuses, and with Guillian–Barré syndrome in adults, and has generated worldwide concern.
