Cusabio) SARS-CoV-2 Antibodies for Variants Detection to Help You on Variants or Antibody Design
작성자
abbabio
작성일자
2021-11-25
조회수
319
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Although SARS-CoV-2 vaccines have been used for prophylactic vaccination of populations, the multiple SARS-CoV-2 variants have led to a weakened effect of neutralising antibodies in patients, resistance to protective antibodies, and even immune escape. Data from GISAID says that the SARS-CoV-2 variants are still evolving, particularly, the major proteins N (Nucleoprotein) and S (Spike glycoprotein) showed high levels of site-specific mutations. The research on SARS-CoV-2 variants has now attracted a great deal of attention from researchers and drug companies worldwide. These variants have complexities in terms of infectivity and antibody responsiveness. The impact of transmission, virulence, and antigenicity of these variants needs to be further investigated and determined.
CUSABIO has developed a series of SARS-CoV-2 N (Nucleoprotein) and S (Spike glycoprotein) antibodies with excellent affinity and specificity.
From our validation data, our SARS-CoV-2 N (Nucleoprotein) antibody CSB-RA33255A1GMY can recognize the Recombinant Human Novel Coronavirus Nucleoprotein with mutations of D3L, R203K, G204R, S235F, T205I, P80R, P13L, D103Y, S202N, L230F, I292T, Q384H, R203K, G204R, R203M, D377Y, D63G.
From our validation data, our SARS-CoV-2 S (Spike) antibody CSB-RA33245A1GMY can recognize the Recombinant Human Novel Coronavirus Spike glycoprotein with mutations of E484K, K417N, N501Y, K417T, D614G.
We are sure CUSABIO SARS-CoV-2 recombinant antibodies can help researchers to better conduct research on variants or accelerate antibody design and vaccine updates.
The Binding Activity of N protein with N Recombinant Antibody. Activity: Measured by its binding ability in a functional ELISA. Immobilized N at 2 μg/mL can bind N Recombinant Antibody (CSB-RA33255A1GMY), the EC50 of N Recombinant Antibody.
The Binding Activity of S protein with S Recombinant Antibody. Activity: Measured by its binding ability in a functional ELISA. Immobilized S at 2 μg/mL can bind S Recombinant Antibody, the EC50 of S Recombinant Antibody (CSB-RA33245A1GMY).
As the COVID-19 pandemic evolves, we are with you during these turbulent times. CUSABIO appreciates the critical role that you and our products play in research efforts to further scientific innovation and discovery. We know that many scientists are diligently pursuing their research throughout the pandemic. Our customer service and technical support teams are equipped to remain available to help with your research needs and answer any questions.
