10 Reagents that Accelerated Research in 2021 Each year we enjoy looking back at how the reagents in our catalog helped contribute to scientific progress over the past year. Read our new blog post to learn about 10 unique reagents that were used in peer-reviewed research in 2021 to further our understanding of science and disease. Many of these reagents were cited in literature in 2021, used to fight the COVID-19 pandemic or are opening new avenues for research in their unique fields. Some of the highlighted reagents include the SpyTag/SpyCatcher Protein Coupling Reagents, Delta-G-VSV System, S9.6 Antibody, Anthrax Protein Variants and more.
Biosensor Proteins and Buffers to Improve Zinc Ion Quantitation With the discovery of zinc transcription factors and zinc transporters with clinical applications, new reagents have been developed to facilitate research into zinc biology. In particular, researchers have needed sensitive, selective and fast-acting tools to measure and image zinc ions. Our provider, Richard Thompson, PhD, has been working for years to address these challenges. He founded the company Pokegama Technologies to improve access to his unique set of zinc reagents. Read our interview with Dr. Thompson on our blog and check out his reagents in our catalog, including three fluorescent zinc biosensor proteins and two MetalloBuffer¢â buffer kits.
New Provider Research It¡¯s always exciting to see new research come from our Kerafast providers! We recently saw a study from Dr. Scot Kimball at Penn State College of Medicine. His puromycin antibody, available in our catalog, is cited in this study about protein synthesis and oxidative metabolism. Another study from Dr. Yu Leo Li at University of Michigan about cancer-specific signaling and effector CD8+ T-cell exhaustion cites his murine squamous cell carcinoma cell line, also available in our catalog. If you are a Kerafast provider or customer, don¡¯t forget to contact us and submit your publications to be featured.
Sequencing & __Expression__ of Monoclonal Antibodies from a Polyclonal Goat Sample Our sister company, Absolute Antibody, has a new research poster that reports the de novo sequencing of moncolonal antibodies from a polyclonal goat antibody sample by mass spectrometry, followed by recombinant __expression__ and testing. To our knowledge, this is the first report of a success conversion of a goat polyclonal to a monoclonal using just antibody protein as a template. Read more about the study and download a copy of the poster here.
Featured Lab
Marina Tanasova, PhD, Michigan Technical University The Tanasova lab research focuses on developing molecular probes and biochemical assays for identifying and understanding the links between impaired biological mechanisms and cancer. The team uses chemical biology to better understand molecular interactions that control cellular equilibrium. They also use synthetic organic chemistry to produce small molecules, like their Multicolor GLUT5-Permeable Fluorescent Probes, used to monitor biochemical processes. These probes, available in the Kerafast catalog, are fluorescent sugar conjugates useful for the analysis of fructose transport.