[Creative Diagnostics] New Gamma-Irradiation Inactivated Antigens Now Availiable!
작성자
abbabio
작성일자
2022-05-25
조회수
447
Newsletter May, 2022
Gamma-irradiation Inactivated Antigens
The most widely used vaccines are prepared by chemical inactivation. However, chemically modified antigenic structures of viruses have been demonstrated to associate with adverse effects, including reduced protection efficacy, unexpected immune responses, and enhanced disease exacerbation. Gamma-irradiation has been investigated as an alternative inactivation method for vaccine production as it is relatively simple, cost-effective, and does not require the use of toxic chemicals. Gamma-irradiation possesses great features to completely inactivate viruses while retaining the structures of protein antigens and cross-protective ability against heterologous strains. Thus, the gamma-irradiation technique is used to develop inactivated whole-cell vaccines for various tricky pathogens.
Creative Diagnostics offers a series of gamma-irradiation inactivated antigens to diagnose specific antibodies response after pathogen infection and to monitor the level of protective neutralizing antibodies after vaccination.
Our range of vaccine R&D reagents covers more than 40 native antigens for key infectious pathogens, including Corynebacterium diphtheriae, Clostridium tetani, Enterovirus, Hepatitis virus, Influenza virus, Poliovirus, Rotavirus, Streptococcus pneumoniae, and Zika virus.
Varicella Zoster Virus (VZV) belongs to the family of herpesviridae. VZV is also known as the chickenpox virus, varicella virus, zoster virus, and human herpesvirus type 3 (HHV-3), which can cause chickenpox (varicella) and shingles (herpes zoster) diseases. Chickenpox most frequently affects children, teens, and young adults, while shingles are more common in older adults.
