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제목 [Cusabio] Available now! Target Proteins for Monkeypox, Smallpox, Cowpox, and Chickenpox Virus Resea
작성자 abbabio
작성일자 2022-06-23
조회수 317
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Monkeypox, another challenge facing humanity

The COVID19 has not receded, and monkeypox has risen again. According to the latest news on the WHO official website, as of June 8, 2022, 1285 laboratory confirmed cases of monkeypox have been reported in 28 countries. Many of the confirmed and suspected cases of monkeypox have not been to the epidemic area, and the infection route of the patients is not yet clear.

In fact, monkeypox is a rare viral disease that is rarely found outside of Africa and does not spread easily from person to person. Given that, it has alarmed scientists and sent them racing for answers (Click to know more about Monkeypox):

CUSABIO responded urgently and organized a series of scientific research reagents related to Monkeypox virus and other pox virus including Smallpox, Chickenpox, Cowpox.

>> Monkeypox

Target TypeTargetCodeProduct NameSpecies
Target of virus-host interactionAPOBEC3ACSB-EP001921HURecombinant Human DNA dC->dU-editing enzyme APOBEC-3A(APOBEC3A)Human
APOBEC3ACSB-YP001921HURecombinant Human DNA dC->dU-editing enzyme APOBEC-3A(APOBEC3A)Human
APOBEC3CCSB-EP889097HURecombinant Human Probable DNA dC->dU-editing enzyme APOBEC-3C(APOBEC3C)Human
APOBEC3GCSB-CF888025HURecombinant Human DNA dC->dU-editing enzyme APOBEC-3G(APOBEC3G)Human
Targets of monkeypox virusA30LCSB-EP848659MHVRecombinant Viral replication protein A28-like(A30L),partialMonkeypox virus
A42RCSB-EP837687MHVRecombinant Profilin(A42R)Monkeypox virus
A46RCSB-EP844975MHVRecombinant Cu-Zn superoxide dismutase-like protein(A46R)Monkeypox virus
D10LCSB-EP837688MHVRecombinant Probable host range protein 2(D10L)Monkeypox virus
E8LCSB-EP844976MHV1Recombinant Cell surface-binding protein(E8L) ,partialMonkeypox virus
I1LCSB-EP855308MHVRecombinant Telomere-binding protein I1(I1L)Monkeypox virus
p28CSB-EP840818MHVRecombinant E3 ubiquitin-protein ligase p28-like(p28)Monkeypox virus
RPO132CSB-EP851803MHVRecombinant DNA-directed RNA polymerase 132 kDa polypeptide(RPO132), partialMonkeypox virus
TKCSB-EP023577MHVRecombinant Thymidine kinase(TK)Monkeypox virus
VITF3LCSB-EP823719MHVRecombinant Intermediate transcription factor 3 large subunit(VITF3L)Monkeypox virus

>> Smallpox, Cowpox, and Chickenpox

OrthopoxvirusGene NameCodeProduct Name__Expression__ Region
Smallpox
(Click for all)		A27LCSB-MP2678VARRecombinant Variola virus A27L protein(A27L)1-194aa
A27LCSB-EP2678VARRecombinant Variola virus A27L protein(A27L)1-194aa
A27LCSB-MP335866VARRecombinant Variola virus 14 kDa fusion protein(A27L)1-110aa
Chickenpox
(Click for all)		gECSB-CF362630VAPRecombinant Varicella-zoster virus Envelope glycoprotein E(gE)31-623aa
gHCSB-EP357614VAPRecombinant Varicella-zoster virus Envelope glycoprotein H(gH),partial18-317aa
gLCSB-EP864287VAQRecombinant Varicella-zoster virus Envelope glycoprotein L(gL)23-160aa
Cowpox
(Click for all)		VACWR025CSB-YP302389VAIRecombinant Vaccinia virus Complement control protein C3(VACWR025)20-263aa
K3LCSB-EP321831VAARecombinant Vaccinia virus Protein K3(K3L)1-88aa
VACWR034CSB-EP323585VAIRecombinant Vaccinia virus Protein K3(VACWR034)1-88aa
VACWR034CSB-YP323585VAIRecombinant Vaccinia virus Protein K3(VACWR034)1-88aa
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