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Presently, Antibody-Drug Conjugate (ADC) has achieved appreciable advances, particular in the therapy for solid or hematological tumors. ADC approach was designed to incorporate antibodies and cytotoxic molecules, which could increase the effectiveness of chemotherapy and reduce its toxicity. Given the proven success of approved ADC drugs, many researchers and pharmaceutical companies give special attention to the potent targets of ADC. In this regard, it was shown that HER2 is the most favorable target for ADC drug design, followed by many CD molecules and other popular targets such as FOLR1, MSLN, CLDN18. Apparently, interests in targets that suggest a more potential for ADC is growing. (Enjoy to Read ADC Targets Article)
To fully support the research and pharmaceutical companies in ADC or drug development, CUSABIO presents a series of ADC highly potent target products, including the most popular targets HER2, MS4A1, TACSTD2, FOLR1, MSLN, CLDN18, TF, NECTIN4, ALCAM; the popular CD molecules CD19, CD22, CD276, CD33, CD37 etc., to help you in ADC investigation or ADC new drug research. (See the table below for details)
Based on the SEQUEST from database of E.coli host and target protein, the LC-MS/MS Analysis result of Human CA9 (Cat. No. CSB-EP614990HUc0) could indicate that this peptide derived from E.coli-expressed Human CA9.
Based on the SEQUEST from database of E.coli host and target protein, the LC-MS/MS Analysis result of Human CASP3 (Cat. No. CSB-EP004548HU) could indicate that this peptide derived from E.coli-expressed Human CASP3.
● High bioactivity verified by functional ELISA
Immobilized human CD48 (Cat. No. CSB-MP004941HU) at 2 μg/mL can bind Anti-CD48 rabbit monoclonal antibody, the EC50 of human CD48 protein is 0.5806-0.8463 ng/mL.
Immobilized human DLL3 (Cat. No. CSB-MP882142HU) at 2 μg/mL can bind Anti-DLL3 Recombinant Antibody (CSB-RA882142A1HU), the EC50 is 1.102-1.707 ng/mL.
Human TNFSF13B protein Fc tag (CSB-MP897523HU1) captured on COOH chip can bind Human BCMA protein Fc tag (Cat. No. CSB-MP023974HU1) with an affinity constant of 39 nM as detected by LSPR Assay.
