[Cusabio] Nanoparticle platform：enhance immune response, display the correct structure, and have com
작성자
abbabio
작성일자
2022-11-21
조회수
252
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Nanoparticle platform
It is difficult for small molecular weight proteins to generate an immune response due to their small molecular weight. Although the fusion of large tags can enhance the immune response, the structure of the target protein will also change, making it difficult to display the correct structure, and most of the immune generated antibodies are also antibodies that recognize tags.
CUSABIO has specially built a Nanoparticle technology platform based on HEK293 __expression__ system, which can enhance immune response, display the correct structure, and have complete biological activity.
Platform Advantage:
✔ Display native conformation with full biological activity
✔ Can enhance immune response
✔ Can be used directly for phage screening (provide empty Nanoparticle for reverse screening)
✔ Can be used for immuno/ELISA/SPR/BLI/cell experiments
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Activity
Measured by a functional ELISA. Immobilized human CD24 at 2 μg/ml can bind anti-CD24 recombinant Monoclonal Antibody(CSB-RA004902A0HU) , the the EC50 is 5.409-8.219 ng/ml.
CUSABIO appreciates the critical role that you and our products play in research since many scientists are diligently pursuing their research to further scientific innovation and discovery. Our customer service and technical support teams are equipped to remain available to help with your research needs and answer any questions.
