[Cusabio] You Must Know the Research Hot-spot - Immune Checkpoint
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abbabio
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2019-05-02
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192
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Immune checkpoints are regulators of immune activation by regulating the antigen recognition of T cell receptor (TCR) in the process of immune response. They play a key role in maintaining immune homeostasis and preventing autoimmunity. Here, we collect a series of common questions and present them on the table below:
What Are Immune Checkpoints?
Immune checkpoints, molecules in the immune system, are regulators of immune activation by regulating the antigen recognition of T cell receptor (TCR) in the process of immune response. They play a key role in maintaining immune homeostasis and preventing autoimmunity. Read More>>
What Are Immune Checkpoint Proteins?
Immune checkpoint proteins refer to a series of proteins coded by the gene of immune checkpoints. They play an important role in the field of cancer immunotherapy research, which is a series of molecules that produce co-stimulatory or inhibitory signals in immune responses. Read More>>
What Are Immune Checkpoint Inhibitors?
Our immune system keeps us from disease, killing bacteria and viruses. T cell is one main type of immune cell. Proteins on the surface of T cells, called immune checkpoints, aim to turn on an immune response or turn it off. Read More>>
What Is Immune Checkpoint Therapy?
Immune checkpoint therapy, mainly including anti‑CTLA‑4 therapy and anti‑PD‑1/PD‑L1 therapy, which targets regulatory pathways in T cells to enhance antitumor immune responses by blocking the inhibitory signals of the immune system. Read More>>
What Are Immune Checkpoint Pathways?
Immune checkpoints are important immune regulators in maintaining immune homeostasis and preventing autoimmunity and consist of inhibitory and stimulatory pathways that maintain self-tolerance and assist with immune response. Read More>>
