CedarLane Expo is Toronto’s premier life science industry show. This year’s event will be held on May 23, at the MaRS Centre, South Tower Auditorium, 101 College Street, Toronto.
Come to this free event to see what’s new in the fields of stem cells, immunology, molecular biology, virology, diabetes, obesity, cancer research, and more! Talk directly with suppliers and discuss your projects with the product experts of Bachem!
We invite you to visit us at our Booth: we are excited to meet with you and learn your needs for peptides. Let us discuss how Bachem can assist to advance your research!
We look forward to meeting you at CedarLane Expo 2019!
Cyclic peptides play key roles in various processes and have excellent potential as therapeutics. Examples of cyclic peptide drugs are the hormone oxytocin and the immunosuppressant cyclosporine A. Cyclic peptides possess several favorable properties as therapeutics. They display a large surface area, which leads to high affinity and selectivity for protein targets and their limited conformational flexibility reduces the entropic penalty upon binding, which in turn improves their binding properties.
Naturally occurring cyclic peptides continue to be an inspiration for peptide drug design due to their resistance to enzyme degradation and enhanced protein binding affinity. Cyclic peptides often have better biological activity compared to linear peptides due to conformational rigidity. In recent years, this class of molecules has been propelled forward by the development of new methods to improve the drug-like properties of peptides by constraining their structure and the creation of new platforms to screen large libraries of cyclic molecules.
This month's highlights include news about brominated tryptophan-containing peptides from marine animals, a peptide that shows promise for protecting kidneys from nephritis, a new approach to treat eye cancer, and a collagen IV-derived peptide that provides a new therapeutic approach for retina diseases.
Marketing Dr. Martina Diekmann Vice President Global Marketing martina.diekmann@bachem.com cell +41 79 945 9107 Marketing Stefan Andlauer, EMBA Director Science & Relationship Marketing stefan.andlauer@bachem.com phone +41 58 595 2107
