[Cusabio] NEW! EGFR-Facilitation of Tumor Growth&Spread!
작성자
abbabio
작성일자
2019-06-27
조회수
461
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EGFR, also known as receptor tyrosine kinase, binds ligands of the EGF family and activates several signaling cascades to convert extracellular cues into appropriate cellular responses.
Known ligands include EGF, TGFA/TGF-alpha, EPGN, BT, EREG and HBEGF. Ligand binding triggers receptor homo- and/or hetero-dimerization and autophosphorylation on key cytoplasmic residues.
Accumulating evidence has revealed that overexpression of EGFR plays an important role in the progression of malignant tumors. In many human malignant tumor tissues and tumor cell lines, EGFR expression and dysfunction exist. For this reason, it is always a hot point of research.
Here, CUSABIO provides an EGFR protein with high purity and activity validated. As known to all, CUSABIO has a strict process of quality control. You can buy CUSABIO products with confidence, it won’t let you down.
The Show of Product
Product Name: Recombinant Human Epidermal growth factor receptor(EGFR),partial
Code: CSB-MP007479HU
SpPurity: Greater than 90% as determined by SDS-PAGE
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Activity
Measured by its binding ability in a functional ELISA. Immobilized EGFR at 1 μg/ml can bind human EGFR antibody, the EC50 of human EGFR protein is 2.867-3.571 ng/ml.
